Stimulatory G protein, animation

Videonummer 11936019
Stimulatory G protein. Animation showing the mechanism by which a stimulatory G protein (red and yellow) mediates the activation of adenylate cyclase (blue) and the opening of a membrane channel (brown). A hormone molecule (orange) binds to its receptor (purple), forming a hormone-receptor complex. This complex binds to the G protein and induces the release of GDP (guanosine diphosphate) from the protein. This allows GTP (guanosine triphosphate) to bind to the G protein instead, causing the alpha subunit (red) of the G protein to disassociate from the beta/gamma subunit (yellow). The alpha subunit-GTP complex then activates adenylate cyclase. Adenylate cyclase is an enzyme that catalyses the formation of cAMP (cyclic adenosine monophosphate, pink), a secondary messenger. Here cAMP then activates a ligand that binds to a membrane channel, which opens it. For a version of this clip without text, see K004/0315.
Lizenzart: Lizenzpflichtig
Credit: Science Photo Library / Biocosmos / Francis Leroy & Maxime Deroyer
Modell-Rechte: nicht erforderlich
Länge: 25 Sekunden
Seitenverhältnis: 16:9
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