i-motif DNA structure, illustration

Bildnummer 12505527
i-motif DNA structure, illustration
i-motif DNA structure (bottom right), computer illustration. The intercalated motif (i-motif) structure is a four stranded knot of DNA (deoxyribonucleic acid) that forms in cytosine-rich regions of a DNA molecule. Cytosine is one of the four nucleotide bases of DNA. When forming a double helix, cytosine bonds only with guanine. However, in i-motif structures two cytosine bases bond to each other. These structures were first seen in human cells in 2018, when an antibody (y-shaped molecule) was found that recognises them. i-motif structures are thought to have a regulatory role in the genome.
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Credit: Science Photo Library / KEITH CHAMBERS
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